0439 Patient-Reported Experience with Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea – Influence of symptom improvements

Abstract Introduction Hypoglossal Nerve Stimulation (HNS) is routinely used as an alternative treatment for patients with obstructive sleep apnea (OSA). Significant and clinically relevant improvements in disease severity OSA symptoms such daytime sleepiness well overall quality of life have been reported randomized-controlled trials large real-world cohort studies. However, so far little data exists on patient-relevant experience the treatment. Methods A structured survey 22 questions was constructed using five-level Likert scales (1 = no agreement, 5 complete agreement) to evaluate patient HNS dimensions “Overall therapy”, “Experience process” “Side effects”. Additional collected current symptom status history. Results 45 from Germany that received a breathing-synchronized system were enrolled (mean age 57.8 years, 78% male). Two-thirds participants had history years or longer (67%). Of all patients, 76% normalized at time study (ESS: 6.4 ± 5.0) 97.6% reporting every night use stimulation therapy. Patients sleepiness, significantly more positive across major domains investigated, compared residual (ESS ≤ 10 versus ESS > 10). therapy tolerated though higher values less often waking up Only 2.2% side effects made them reduce even discontinue Conclusion Overall patient-reported high satisfaction process observed. Subjective influenced by under stimulation. Side occur, but rarely impact subjective use. studies are warranted confirm findings this evaluation larger cohorts. Support (if any)